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教师简介

丁毅
来源:伟德官网 时间:2016-12-26 11:47:33 阅读量:
职称职务:教授、博士生导师
出生年月: 1956年
学  位: 博士学位
学科专业: 遗传学、植物发育生物学
实验室位置:生科大楼3002室
联系方式:027-68754319(O)
Email:  yiding@whu.edu.cn

 

主要研究方向:
1.植物细胞分子遗传学
2.植物基因组与分子进化遗传学
3. 植物基因组学与蛋白质组学


教 学:

1. 主讲生科院本科生基础课《遗传学》、全校通识课《现代生命科学导论》;研究生课《分子遗传学》、《现代遗传学》等;

2. 与路铁刚主编 《分子遗传学》2008年,高教出版社;参编教材:《现代生命科学概论》,2001年,高教出版社;《遗传学(第二版)》,2008年,高教出版社;《遗传学(第3版)》副主编,2016年,高教出版社。
3. 丁毅 王建波 主编《遗传学实验教程(第2版)》,2019年,高教出版社。

主持科研项目:

1. 国家自然科学基金项目:水稻新型不育系武香S育性转换分子机理与应用基础研究(31471464,2015-2018)
2. 国家自然科学基金项目:中国莲基因组遗传图谱的构建和连锁群染色体定位(31271310,2013- 2016)
3. “973”子项目(2013CB126900,2013-2017)
4. 国家自然科学基金项目:杂交水稻同核异质雄性不育系败育的分子机理与应用研究.(30971740,2010-2012)
5. “973”子项目:(2007CB108705,2007-2012)
6. 国家自然科学基金项目:中国莲种质资源SSR分子标记筛选及其应用基础研究.(30771152,2008-2010)
7. 国家自然科学基金项目:云南紫稻细胞质雄性不育系胞质的遗传基础与利用. (30571143,2006-2008)
8. 国家自然科学基金项目:新型紫稻细胞质雄性不育系的遗传机理与应用基础研究. (30340079,2004-2005)
9. 国家自然科学基金项目:中国近缘野生大麦基因组的遗传多样性研究. (30270709,2003-2005)
10. 国家自然科学基金项目:西藏大麦属植物的系统与进化—带型RAPD和原位杂交分析 (39670051,1997—1999)

获 奖:
1. 2011年湖北省科技进步一等奖一项(排名5);
2. 2010年度武汉市科技进步奖二等奖一项(2010J-118-2-42-035-01);
3. 2009年获农业部中华农业科技奖二等奖一项(KJ2009-G2-012-08);
4. 2009年获湖北省高等学校教学成果奖三等奖一项(排名1);
5. 2002年获国家技术发明二等奖一项(排名5);
6. 1997年获国家教委科技进步二等奖一项(排名3);


获国家发明专利:
1. 水稻无花粉细胞质雄性不育系的选育方法,专利号 ZL99120003.9
2. 具有叶片标记性状的三系杂交水稻不育系的选育方法,专利号ZL97109237.0
3. 杂交水稻三系超级稻恢复系的选育方法,专利号:ZL 00 1 31189.1
4. 耐高温抗倒伏红莲型细胞质雄性不育系的选育方法,专利号:ZL200710053381.X
5. 一种鲁棒有序的mRNA差异显示的方法,专利号:ZL 200910063161.4
6.一种选育杂交水稻光(温)敏核不育系的方法,专利号:ZL 201210288218.2

近5年代表性科研论文:

1. Ying Wang, Zeyang Xiong, Qian Li, Yueyang Sun, Jing Jin, Hao Chen, Yu Zou, Xingguo Huang and Yi Ding*. Circular RNA profiling of the rice photothermosensitive genic male sterile line Wuxiang S reveals circRNA involved in the fertility transition. BMC Plant Biology 2019, 19:340  | doi.org/10.1186/s12870-019-1944-2


2. Hao Chen, Jing Jin, Hongyuan Zhang, Ying Wang, Qian Li, Yu Zou, Xingguo Huang, Baojin Zhou, Ruo Zhou and Yi Ding*. Comparative Analysis of Proteomics and Transcriptomics during Fertility Transition in a Two-Line Hybrid Rice Line Wuxiang S. Int. J. Mol. Sci. 2019, 20(18): 4542; | doi:10.3390/ijms20184542


3.
Jing Jin, Songtao Gui, Qian Li, Ying Wang, Hongyuan Zhang, Zhixuan Zhu, Hao Chen, Yueyang Sun, Yu Zou, Xingguo Huang and Yi Ding*. The transcription factor GATA10 regulates fertility conversion of a two-line hybrid tms5 mutant rice via the modulation of UbL40 expression. Journal of Integrative Plant Biology 2019, | doi: 10.1111/jipb.12871


4. Songtao Gui, Jing Peng, Xiaolei Wang, Zhihua Wu, Rui Cao, Jér?me Salse, Hongyuan Zhang, Zhixuan Zhu, Qiuju Xia, Zhiwu Quan, Liping Shu, Wedong Ke and Yi Ding1*.Improving Nelumbo nucifera genome assemblies using high-resolution genetic maps and BioNano genome mapping reveals ancient chromosome rearrangements. The plant journal 2018, 94
4:721-734|  DOI:10.1111/tpj.13894


5.  Yinzhen Zheng, Junjie Yan, Shuzhen Wang, Meiling Xu, Keke Huang, Guanglong Chen and Yi Ding*. Genome-wide identification of the pectate lyase-like (PLL) gene family and functional analysis of two PLL genes in rice. Molecular Genetics and Genomics 2018, 293(6):1317-1331 | DOI
10.1007/s00438-018-1466-x


6. Guanglong Chen, Yu Zou, Jihong Hu* and Yi Ding*. Genome-wide analysis of the rice PPR gene family and their expression profiles under different stress treatments. BMC Genomics 2018, 19:720   | doi.org/10.1186/s12864-018-5088-9


7.Jihong Hu, Tao Zeng, Qiongmei Xia, Qian Qian, Congdang Yang, Yi Ding*, Luonan Chen*, Wen Wang*. Unravelling miRNA regulation in yield of rice (Oryza sativa) based on differential network model. Scientific reports 2018, 8:8498


8. Zhixuan Zhu, Songtao Gui, Jing Jin, Rong Yi, Zhihua Wu, Qian Qian and Yi Ding*. The NnCenH3 protein and centromeric DNA sequences profile of sacred lotus (Nelumbo nucifera Gaertn.) reveal the DNA structures and dynamics of centromeres in basal eudicots. The plant journal 2016, 87568–582  | doi: 10.1111/tpj.13219


9. Yubo Zhang and Yi Ding*. Dynamics Simulation and Bioinformatics Study on chloroplast stromal ridge complex from rice (Oryza sativa L.). BMC Bioinformatics 2016, 17:28 | DOI 10.1186/s12859-016-0877-0


10. Songtao Gui, Zhihua Wu, Hongyuan Zhang, Yinzhen Zheng, Zhixuan Zhu, Dequan Liang and Yi Ding*. The mitochondrial genome map of Nelumbo nucifera reveals ancient evolutionary features. Scientific reports 2016, 6:30158 | DOI: 10.1038/srep30158


11. Hongyuan Zhang, Jihong Hu, Qian Qian, Hao Chen, Jing Jin, and Yi Ding*. Small RNA profiles of the rice PTGMS line Wuxiang Sr eveal miRNAs involved in the fertility transition. Frontiers in Plant Science 2016, 7: 514 | DOI: 10.3389/fpls.2016.00514


12. Jihong Hu, Guanglong Chen, Hongyuan Zhang, Qian Qian, and Yi Ding*. Comparative transcript profiling of alloplasmic male-sterile lines revealed altered gene expression related to pollen development in rice (Oryza sativa L.). BMC Plant Biology 2016, 16:175 | DOI 10.1186/s12870-016-0864-7  


13. Jihong Hu, Jing Jin, Qian Qian, Keke Huang and Yi Ding*. Small RNA and degradome profiling reveals miRNA regulation in the seed germination of ancient eudicot Nelumbo nucifera. BMC Genomics 2016, 17 (1):684| DOI:10.1186/s12864-016-3032-4


14. Junjie Yan, Hongyuan Zhang, Yinzheng Zheng,and Yi Ding*. Comparative expression profiling of miRNAs between the cytoplasmic male sterile line MeixiangA and its maintainer line MeixiangB during rice anther development. Planta 2015, 241:109-123 | DOI: 10.1007/s00425-014-2167-2


15. Jihong Hu, Xiaojun Chen, Hongyuan Zhang, and Yi Ding*. Genome-wide analysis of DNA methylation in photoperiod- and thermo-sensitive male sterile rice Peiai 64S. BMC Genomics 2015,16:102 |DOI 10.1186/s12864-015-1317-7


16. Jihong Hu, Songtao Gui, Zhixuan Zhu, Xiaolei Wang, Weidong Ke, and Yi Ding*. Genome-wide identification of SSR and SNP markers based on whole-genome re-sequencing of a Thailand wild sacred lotus (Nelumbo nucifera). PLoS ONE 201510(11): e0143765| DOI:10.1371/journal.pone.0143765


17. Qian Qian, Lin Huang, Rong Yi, Shuzhen Wang, Yi Ding*. Enhanced resistance to blast fungus in rice (Oryza sativa L.) by expressing the ribosome-inactivating protein alpha- momorcharin. Plant Science 2014217-218: 1-7


18. Xiaojun Chen, Jihong Hu, Hongyuan Zhang, and Yi Ding*. DNA methylation changes in photoperiod - thermo-sensitive male sterile rice PA64S under the two different conditions. Gene 2014, 537(1):143-148


19. Jihong Hu, Lulu Sun, Zhixuan Zhu, Yuan Zheng, Wei Xiong, and Yi Ding*. Characterization of conserved microRNAs from five different cucurbit species using computational and experimental analysis.  Biochimie 2014,102:137-144


20. Zhihua Wu, Songtao Gui, Shuzhen Wang, and Yi Ding*. Molecular evolution and functional characterisation of an ancient phenylalanine ammonia-lyase gene (NnPAL1) from Nelumbo nucifera: novel insight into the evolution of the PAL family in angiosperms. BMC Evolutionary Biology 2014, 14:100


21. Junjie Yan, Han Tian, Shuzhen Wang, Jinzhen Shao, Yinzhen Zheng, Hongyuan Zhang, Lin Guo, and Yi Ding*. Proteomics analysis identified pollen developmental defects in the rice ZD-CMS line. Journal of Proteomics 2014,108:110-123


22. Rong Yi, Zhixuan Zhu, Jihong Hu, Qian Qian, Jincheng Dai and Yi Ding*. Identification and expression analysis of microRNAs at the grain filling stage in riceOryza sativa L.via deep sequencing. PLoS ONE 2013, 8(3): e57863


23. Jihong Hu, Rong Yi, Hongyuan Zhang, Yi Ding*.Nucleo-cytoplasmic interactions affect RNA editing of cox2, atp6 and atp9 in alloplasmic male-sterile rice (Oryza sativa L.) lines. Mitochondrion 2013,13:87-95


24. Jihong Hu, Hongyuan Zhang, Yi Ding*. Identification of conserved microRNAs and their targets in the model legume Lotus japonicas. Journal of Biotechnology 2013,164:520-524


25. Ying He, Shuzhen Wang, Yi Ding*.Identification of novel glutelin subunits and a comparison of glutelin composition between japonica and indica rice (Oryza sativa L.).Journal of Cereal Science 2013,57:362-371


26. Ying He, Yubo Zhang, Shuzhen Wang. Hanlai Zeng *and Yi Ding*.Characterization of a Novel Glutelin Subunit OsGluBX by the Experimental Approach and Molecular Dynamics Simulations. Appl Biochem Biotechnol 2013,169:1482–1496


27. Shuzhen Wang, Yinzhen Zheng, Xiaojun Chen, Junjie Yan, Zhixuan Zhu, and Yi Ding*. Alpha-momorcharin, a ribosome-inactivating protein fromMomordica charantia, possessing DNA cleavage properties. Protein & Peptide Letters 2013,20(11):1257-1263


28. Jihong Hu*, Lulu Sun, and Yi Ding*. Identification of conserved microRNAs and their targets in chickpea (Cicer arietinum L.).Plant Signaling & Behavior 2013, 8: e23604


29. Yun Wang, Guangyi Fan, Yiman Liu, Fengming Sun, Chengcheng Shi, Xin Liu, Jing Peng, Wenbin Chen, Xinfang Huang, Shifeng Cheng, Yuping Liu, Xinming Liang, Honglian Zhu, Chao Bian, Lan Zhong, Tian Lv, Hongxia Dong, Weiqing Liu, Xiao Zhong, Jing Chen, Zhiwu Quan, Zhihong Wang, Benzhong Tan, Chufa Lin, Feng Mu, Xun Xu, Yi Ding*, An-Yuan Guo*, Jun Wang* & Weidong Ke*.The sacred lotus genome provides insights into the evolution of flowering plants. The Plant Journal2013,76:557-567


30. Jihong Hu, Lei Pan, Honggao Liu, Shuzhen Wang, Zhihua Wu, Weidong Ke, and Yi Ding*. Comparative analysis of genetic diversity in sacred lotus (Nelumbo nucifera Gaertn.) using AFLP and SSR markers. Mol Biol Rep 2012,39:3637–3647


31. Shuzhen Wang, Yubo Zhang, Honggao Liu, Ying He, Junjie Yan, Zhihua Wu, and Yi Ding*. Molecular cloning and functional analysis of a recombinant ribosome-inactivating protein (alpha-Momorcharin) from Momordica charantia. Applied Microbiology and Biotechnology 2012,96:939–950


32. Jun-jie Yan & Yu-bo Zhang & Yi Ding*. Binding mechanism between Hsp90 and Sgt1 explored by homology modeling and molecular dynamics simulations in rice. J Mol Model (2012) 18:4665–4673


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